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Our Paradigm-Shifting Potential:

Prevent Multiple Side Effects, Enhance Quality of Life, Improve Patient Outcomes

Because we harness a universal mechanism common to all healthy, normal cells – p53’s cell cycle regulation – we have the opportunity to protect multiple cells throughout the body from chemotherapy.

A single medicine to protect multiple cell types and prevent multiple side effects would introduce a paradigm shift in cancer patient care.

We believe limiting or preventing side effects will enable patients to avoid serious and life-threating medical events and have a better quality of life while undergoing chemotherapy. In addition, fewer dose delays and dose reductions may also help patients fight cancer more effectively and enhance outcomes.

Our Vision: Chemoprotection for all patients with p53-mutated cancer

≈1M
people in the U.S. are diagnosed each year with p53-mutant cancer
p53
The most common cancer mutation
50%
of all cancer patients have p53-mutated cancer

The p53 mutation is prevalent across most major cancer types, giving us the potential to bring selective chemoprotection to millions of patients.

≈1M
1M people in the U.S. are diagnosed each year with p53-mutant cancer
Ovarian
SCLC
Stomach/Esophagus
Pancreatic
Other Cancers
Bladder
Colorectal
NSCLC
Breast
NSCLC = Non-Small Cell Lung Cancer; SCLC = Small Cell Lung Cancer